Research Interest
We are primarily interested in exploring the genetic and epigenetic basis of Human diseases. Presently the lab has focused on (1) Psoriasis, a chronic inflammatory skin disease, (2) Oral squamous cell carcinoma and (3) oral potentially malignant diseases. The current work is focused on the determination of genetic and epigenetic factors in psoriasis pathogenesis among the patients in India and determination of genetic and epigenetic biomarkers in oral pre-cancer and cancer patients in India.
Ongoing Projects
- miRNAs in regulating the cardinal histopathological features of Psoriasis and their role as molecular checkpoints in cell proliferation; DST-SERB, Govt. of India (2023-2026) [PI: Raghunath Chatterjee]
- To identify the role of genetic and epigenetic alterations in epidermal keratinocytes in the pathogenesis of Psoriasis; DST-SERB, Govt. of India (2021-2024) [CRG/2020/003837] [PI: Raghunath Chatterjee]
- Identification of the contribution of Human Leukocyte Antigen (HLA) alleles and functional coding variants to the risk of psoriasis in patients from West Bengal; DBT, Govt. of WB (2016-2019) [572(sanc)/BT-RD- 09/2015] [PI: Raghunath Chatterjee]
Raghunath Chatterjee
Professor
Email: rchatterjee@isical.ac.in
Research Interest: Genetic and epigenetic basis of Human disease.
Professor
Email: rchatterjee@isical.ac.in
Research Interest: Genetic and epigenetic basis of Human disease.
completed Projects
- Identification of Genetic and Epigenetic Associations Among Psoriasis patients in India; DST-SERB, Govt. of India (2016-2019) [EMR/2015/002436] [PI: Raghunath Chatterjee]
- Non-invasive identification and validation of Epigenetic biomarker in saliva for early detection of Oral pre-cancer and cancer patients in India; CSIR, Govt. of India (2015-2016) [No. 27(0306)/14] [PI: Raghunath Chatterjee]
- Statistical methods to detect epistasis and gene-environment interactions in genetic association studies; DST-SERB, Govt. of India (2014-2017) [PI: Indranil Mukhopadhyay; Co-PI: Raghunath Chatterjee]
- Determination of polymorphisms in the MHC Class I genes and their associations among psoriasis patients of Eastern India; ICMR, Govt. of India (2015-2017) (Grant No. 67/08/2014-IMM/BMS) [PI: Raghunath Chatterjee; RA: Anamika Das]